A fluorescent probe for detection of histone deacetylase activity based on aggregation-induced emission.
نویسندگان
چکیده
A tetraphenylethylene-derivative fluorescent probe for the one-step detection of histone deacetylases (HDAC) was developed. The deacetylation of the probe triggers electrostatic interaction between the molecules and automatically leads to fluorescence enhancement based on aggregation-induced emission (AIE).
منابع مشابه
Real-time detection of histone deacetylase activity with a small molecule fluorescent and spectrophotometric probe
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عنوان ژورنال:
- Chemical communications
دوره 48 94 شماره
صفحات -
تاریخ انتشار 2012